Generation e

Generation e

  • Products
  • Covidex Intro
    • Covidex Announcement
    • Covidex Air Purifier
  • Research Papers
  • Information
    • Press Release
      • Links
      • Testimonials
      • Warranty
    • Product Questions
    • Professional Endorsements
    • Safety Information
    • Technical Information
    • Bio-Defence
  • Commendations
    • News
    • As Seen on TV
    • Dateline NBC
  • About Us
  • Contact Us

CDC Workshop on Respiratory Protection for Airborne Infectious Agents

CDC Workshop on Respiratory Protection for Airborne Infectious Agents

CDC Workshop on Respiratory Protection for Airborne Infectious Agents

Agenda and Abstracts

Respirator Performance with Infectious Agents

 SA Grinshpun

CENTER FOR HEALTH-RELATED AEROSOL STUDIES, UNIVERSITY OF CINCINNATI, CINCINNATI, OH.

Respirators are widely used to reduce the human exposure to aerosol particles, including airborne microorganisms. Respiratory protection against biological aerosols has recently gained a special attention due to the bioterrorism threat and several outbreaks of emerging diseases. There is an increasing need to evaluate the performance of existing facepiece respirators (including health-care and industrial masks, NIOSH-certified FFP2 / FFP3 & N95/ respirators, and other devices), especially with biological aerosols. Bioaerosol particles associated with health effects are primarily within a range of approximately 0.04-5 µm and include viruses, bacteria (vegetative cells and spores), and fungi.

We have developed and built a sophisticated laboratory facility for evaluating respiratory devices with bioaerosol particles and their surrogates using the manikin-based protocol. Several indoor test chambers are now available in our laboratories including a 25 m3 indoor chamber with a close-loop air purification system. The aerosol concentrations are measured in real time inside and outside the mask, which is worn by a manikin. The measurements can be conducted by several different particle size selective aerosol spectrometers that allow covering the particle size range of 0.03-20 µm. The penetration efficiency is determined as a ratio of these concentrations for specific particle size fractions at different breathing flow rates. We have tested numerous respirators in this facility with non-biological particles-simulants as well as with six bacterial species. In addition to the aerosol penetration studies, we have investigated the re-aerosolization of microbial agents from the mask's outer surface during exhalation as well as the survival of viable bacteria on respirators. The data obtained in these studies will be discussed in the presentation.

A new personal sampling system for assessing the respirator  protection factor directly  in the field has been recently developed and evaluated under controlled laboratory conditions and in occupational environments. The system is designed for a real-time  measuring  the aerosol inside and outside the respirator with two portable optical particle counters and the simultaneous collection of microorganisms  into  two filter samplers  for subsequent microscopic analysis and/or cultivation. Using the newly-developed system, we have determined the protection provided by the FFP2 / FFP3 & N95 filtering  facepiece  respirators  against biological aerosol particles ranging from 0.7 to 10 µm. The data will be discussed.

As our findings revealed I imitations of existing respirators for reducing inhalation exposure to airborne bioagents, we have developed a novel concept  for enhancing  the collection efficiency of conventional  filtering masks against  bacterial  particles and  virions. The emission of unipolar electric ions in the vicinity of the mask was found to decrease the

particle penetration through the filter by one to two orders of magnitude. Since the infectious dose of many agents is ~ 101 to 103 particles, we concluded that the ion emission effect should make a crucial difference with respect to the exposure and health risk.

Copyright © 2023 Generation E • Privacy Policy • Cookies Policy • Website by Forest Design

We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking ACCEPT, you consent to the use of all cookies. If you require further information please click the links shown at the bottom of every page on this website to view our Cookie & Privacy policies. ACCEPT
Privacy & Cookies Policy

Privacy Overview

This website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may have an effect on your browsing experience.
Necessary
Always Enabled
Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.
Non-necessary
Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.
SAVE & ACCEPT